All-Nighter · Acute Total Sleep Deprivation通宵 · 一夜未眠

Place · Level 3

16 → 48 h 时间线 · 咖啡因封顶 400 mg · 战略 nap · 单晚 3-7 天恢复 · 8 条年轻没事、咖啡顶拆穿

Timeline · 16 → 48 h

Stop 1/8

一夜未眠时间线 · 16 → 48 h

An all-nighter is not a state, it is a curve. Adenosine, cortisol, prefrontal control, glucose tolerance, and immune function drift out of sync one by one along a timeline that looks roughly like this:

0-16 h (awake into your normal bedtime): adenosine accumulates linearly + occupies A₁/A₂A receptors; the SCN has already signalled the pineal to start melatonin (~21:00-22:00); subjectively you feel "tired but still functional"16-17 h (1-2 am): cognitive performance is equivalent to a blood alcohol of 0.05 % (Dawson 1997 *Nature*) — the legal DUI threshold; reaction speed, attention, and decision circuits all degrade together24 h (a full day without sleep): equivalent to blood alcohol 0.10 %, above DUI; microsleeps — 1-15 s of involuntary disconnection — begin appearing repeatedly during monotonous tasks, and you cannot detect them30-36 h (the next afternoon-evening): an eerie 30-90 min "second wind" — not recovery, but the SCN actively pulling you up inside its wake window (cortisol morning peak + body-temperature rhythm). Use it to close loose ends, not to convince yourself you are fine48 h: microsleeps become routine + emotional stability collapses + working memory drops ~40 %; brief peripheral hallucinations begin in some people — not psychosis, but REM intrusion into wakefulness. This is the stop line.
How to read this island: every segment above is one specific way "adenosine pile-up (process S)" + " misalignment (process C)" play out inside your body. Hold those two lines in mind and the next six scenes line up.

The real question users bring here is "how far along the curve am I, and where are the red lines?" This island draws the curve, then matches each segment to the lever that actually helps.

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