Irritable Bowel Syndrome肠易激综合症 · IBS

Place · Level 3

全球 5-10% · Rome IV 分型 IBS-D/C/M · 低 FODMAP 三阶段 · 肠脑轴 · SIBO 测试陷阱 · 红旗清单

Rome IV · 4 subtypes

Stop 1/5

Rome IV 标准 · 4 种分型

Irritable Bowel Syndrome (IBS) is a functional bowel disorder: structurally the intestine has no visible lesion, but motility / sensation / microbiome / gut-brain axis goes wrong. Globally affects 5-10% of adults, women ~2× men, average diagnostic delay 4 years.

Rome IV criteria (2016)

Core: recurrent abdominal pain, averaging at least 1 day/week, for ≥3 months (onset ≥6 months prior), plus ≥2 of:

Related to defecation (before / after / no change)Associated with change in stool frequencyAssociated with change in stool form
4 subtypes (by Bristol stool scale):

IBS-D (diarrhea): >25% loose/watery, <25% hardIBS-C (constipation): >25% hard, <25% loose/wateryIBS-M (mixed): both loose/watery and hard >25%IBS-U (unclassified): doesn't fit above
Key: IBS is a diagnosis of exclusion

Must rule out: IBD (ulcerative colitis / Crohn's) / lactose intolerance / celiac disease / microscopic colitis / colorectal cancerBasic blood: CBC + + celiac antibodies (tTG-IgA) + Stool: occult blood + (age 40+) calprotectinColonoscopy: age 50+ / family history / red flags
Why a dedicated atlas island?

Severely undertreated: 50% of patients never see a doctor, 60% use OTC ineffectivelyDietary intervention (low FODMAP) actually works, but is extensively misreported (next scene)Marketing hotbed for 'SIBO testing ads' + 'candida detox' + 'leaky gut syndrome'

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本站提供科普与一般性建议，不替代医师诊断或处方；有症状或正在服药请咨询合格医师。 Educational content, not medical advice — consult a clinician for diagnosis or treatment.

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