Perimenopause更年期 · 围绝经期

What & when

Stop 1/6

什么 · 什么时候 · 不是断崖

Menopause is the time point of 12 consecutive months without menstruation, which for most women happens at 51 (median; range 45-58). Perimenopause is the 4-10 year transition preceding it — and that's where most symptoms actually occur.

STRAW+10 criteria (Harlow 2012, globally accepted staging):

Late reproductive (-3): slight cycle change, FSH occasionally elevated, still fertileEarly perimenopause (-2): cycle changes ≥ 7 daysLate perimenopause (-1): ≥ 60 days without periodEnd of transition: 12 consecutive months without period → enters postmenopause
Key: estrogen isn't a straight decline; it fluctuates wildly

Early perimenopause: estrogen can be even higher than reproductive years (anovulatory cycles + elevated FSH → over-response of remnant follicles)Then a cliff-like drop phase (1-3 years)Finally stabilizes at a low (postmenopause)This is why symptoms wax and wane rather than declining smoothly
Typical symptoms (~80% of women experience at least one):

Menstrual cycle changes (shorter / longer / stopped)Vasomotor symptoms (VMS): hot flashes + night sweats (next scene in detail)Sleep disruptionMood swings / anxiety / depression risk upVaginal dryness / dyspareunia'Brain fog' + attention problemsJoint pain / muscle achesWeight + visceral fat rise (even with unchanged diet and exercise)
Why does this deserve its own Atlas island?

Perimenopause is a metabolic turning point in a woman's life: bone mass, cardiovascular risk, and metabolic syndrome risk inflect during these years — not after 65. The Atlas treats it for the first time as 'a life stage that deserves serious attention', not 'something to push through'.

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Perimenopause更年期 · 围绝经期

What & when

Stop 1/6

什么 · 什么时候 · 不是断崖

Read story