The claimEvidence B · meta-analysis
Perimenopause can be managed with supplements alone
The evidence
MHT moves bone density + vasomotor + GSM together; phytoestrogens have scattered effects and don't substitute.
The mechanism, in brief
Menopause is the time point of 12 consecutive months without menstruation, which for most women happens at 51 (median; range 45-58). Perimenopause is the 4-10 year transition preceding it — and that's where most symptoms actually occur.
Sources (2)
- Harlow, S. D., Gass, M., Hall, J. E., Lobo, R., Maki, P., Rebar, R. W., Sherman, S., Sluss, P. M., & de Villiers, T. J. (2012). Executive summary of the Stages of Reproductive Aging Workshop +10: addressing the unfinished agenda of staging reproductive aging. The Journal of Clinical Endocrinology & Metabolism, 97(4), 1159-1168.
- The 2022 Hormone Therapy Position Statement of The North American Menopause Society Advisory Panel. (2022). The 2022 hormone therapy position statement of The North American Menopause Society. Menopause, 29(7), 767-794.