营销话术证据 A · 指南级
他汀耗光 CoQ10，补 CoQ10 能治他汀肌肉痛
真相
机制真 (甲羟戊酸通路)，但 6 RCT、302 人的 meta 显示补 CoQ10 不能可靠缓解肌痛 (Banach 2015)。
机制速览
两个对照的例子, 能帮你分清该补和该错开时间。
来源（2）
- Wiesner, A., Gajewska, D., & Pasko, P. (2021). Levothyroxine interactions with food and dietary supplements - a systematic review. Pharmaceuticals, 14(3), 206. Calcium, iron, and coffee reduce levothyroxine absorption (iron co-ingestion about 33%, coffee about 27-36%); guidance advises an empty stomach and at least 4 hours separation.
- Banach, M., Serban, C., Sahebkar, A., et al. (2015). Effects of coenzyme Q10 on statin-induced myopathy: a meta-analysis of randomized controlled trials. Mayo Clinic Proceedings, 90(1), 24-34. Across 6 RCTs (302 patients), CoQ10 supplementation produced no significant improvement in statin-associated muscle pain or plasma creatine kinase.