营销话术证据 B · meta 分析
胖是基因决定的, 改不了
真相
可遗传度是群体统计不是个人判决. 基因给倾向不给终点; 同一基因组在不同环境里体重天差地别 (Loos & Yeo 2022). 环境与行为有巨大空间.
机制速览
把前面收成一条能带走的认知, 同时关掉两个极端.
来源（3）
- Fothergill, E., Guo, J., Howard, L., Kerns, J. C., Knuth, N. D., Brychta, R., Chen, K. Y., Skarulis, M. C., Walter, M., Walter, P. J., & Hall, K. D. (2016). Persistent metabolic adaptation 6 years after 'The Biggest Loser' competition. Obesity, 24(8), 1612–1619.
- Sumithran, P., Prendergast, L. A., Delbridge, E., Purcell, K., Shulkes, A., Kriketos, A., & Proietto, J. (2011). Long-term persistence of hormonal adaptations to weight loss. The New England Journal of Medicine, 365(17), 1597–1604.
- Loos, R. J. F., & Yeo, G. S. H. (2022). The genetics of obesity: from discovery to biology. Nature Reviews Genetics, 23(2), 120-133. Polygenic (common) and monogenic (rare) obesity share genetic and biological underpinnings, pointing to a central role for the brain in body-weight control.