营销话术证据 B · meta 分析

种子油 (omega-6) 有毒、致炎、致胖

真相

缺人体证据. PUFA 替代饱和脂肪反而降 CHD (Mozaffarian 2010); 食欲假说只到小鼠 (Alvheim 2012). 真问题是油炸 + 包装的食物形态, 不是分子.

机制速览

先说心血管 — 这是 omega-6 争论里证据最多的地方, 结论可能和两派都不完全一样.

来源（2）

Mozaffarian, D., Micha, R., & Wallace, S. (2010). Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Medicine, 7(3), e1000252. Replacing saturated fat with polyunsaturated fat reduced CHD events ~19% (RR 0.81, 95% CI 0.70-0.95), ~10% per 5% energy.
Hooper, L., Al-Khudairy, L., Abdelhamid, A. S., Rees, K., Brainard, J. S., Brown, T. J., et al. (2018). Omega-6 fats for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews, (11), CD011094. Increasing omega-6 fats made little or no difference to cardiovascular events or mortality (low-certainty evidence), with a possible small reduction in myocardial infarction.